Shopping Cart

Remove All
Your shopping cart is currently empty

Fluoxetine hydrochloride

Name: Fluoxetine hydrochloride
Brand: TargetMol
SKU: T0450L
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0450LCas No. 56296-78-7

Alias LY-110140, Lilly110140, Fluoxetine HCl

Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.

Fluoxetine hydrochloride

🥰Excellent

Purity: 99.98%

Catalog No. T0450LAlias LY-110140, Lilly110140, Fluoxetine HClCas No. 56296-78-7

Pack Size	Price	Availability
25 mg	$40	In Stock
50 mg	$55	In Stock
100 mg	$70	In Stock
500 mg	$198	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.98%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
In vitro	When co-administered in adult male SD rats, fluoxetine and olanzapine induce a robust and sustained increase in extracellular dopamine levels, with concentrations surpassing baseline by 361% and 272%, respectively—significantly higher than when either drug is used alone. Additionally, fluoxetine reverses the prolonged latency of escape caused by unavoidable shocks in adult male SD rats.
In vivo	Fluoxetine accelerates the maturation of immature neurons. It enhances the proliferation of new cells in the dentate gyrus of the adult rat hippocampus, strengthens neurodependent long-term potentiation in the hippocampal dentate gyrus, and increases the number of proliferating cells in the prefrontal cortex.
Synonyms	LY-110140, Lilly110140, Fluoxetine HCl

Chemical Properties

Molecular Weight	345.787
Formula	C₁₇H₁₉ClF₃NO
Cas No.	56296-78-7
Smiles	Cl.CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 3.5 mg/mL (10.12 mM), Sonication is recommended.

DMSO: 127 mg/mL (367.28 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (11.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8920 mL	14.4598 mL	28.9195 mL	144.5977 mL
5 mM	0.5784 mL	2.8920 mL	5.7839 mL	28.9195 mL
10 mM	0.2892 mL	1.4460 mL	2.8920 mL	14.4598 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1446 mL	0.7230 mL	1.4460 mL	7.2299 mL
50 mM	0.0578 mL	0.2892 mL	0.5784 mL	2.8920 mL
100 mM	0.0289 mL	0.1446 mL	0.2892 mL	1.4460 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc